Clean day, cleanse day, intermittent fasting, call it whatever you like.  It's torture sometimes, but it's wonderful.  I cannot count the number of doctors, experts, podcasts, articles that support it, but do your own research.  All I know, is that I did it to the letter once in the past 30 days and I walked to work the next day, literally on a cloud, loving life, almost feeling TOO giddy.  I had to stop in my tracks and say 'self, did you just try to complain that you are TOO happy?? Geez, you're tough to please.' and correct.  It's not always easy, but it is simple, and it's worth it.